Separation of the Toxins of Bacillus Dysenteriæ Shiga
نویسندگان
چکیده
By the suppression, through anaerobiosis, of the exotoxin-producing activity of Bacillus dysenteriae Shiga a pure endotoxin is produced directly from the culture. The duality of the poison of Shiga bacillus is further substantiated by studies on the diffusion of exotoxin, or neurotoxin, and endotoxin, or enterotoxin, by means of collodion sacs, implanted intraabdominally in rabbits or placed in vitro.
منابع مشابه
Toxins and Antitoxins of Bacillus Dysenteriæ Shiga
With the methods which have been described we have separated an exotoxin and an endotoxin from cultures of the Shiga dysenteric bacillus. The study of the nature and effect of the poison of this microorganism is thus simplified. The two toxins are physically and biologically distinct. The exotoxin is relatively heat-labile, arises in the early period of growth, and yields an antiexotoxic immune...
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ورودعنوان ژورنال:
- The Journal of Experimental Medicine
دوره 37 شماره
صفحات -
تاریخ انتشار 2004